Synthetic and biosynthetic studies of porphyrins. Part 11. The synthesis of meso oxygenated protoporphyrins
- 1 January 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 2,p. 307-312
- https://doi.org/10.1039/p19870000307
Abstract
Treatment of protoporphyrin IX dimethyl ester (12) with benzoyl peroxide affords a mixture of the four isomeric meso-benzoyloxy derivatives (13). These have been separated by h.p.l.c. and distinguished from each other by hydrolysis to the corresponding oxophlorins (oxyporphyrins), insertion of iron to form the oxyhaems (3), and oxidation by molecular oxygen to the corresponding biliverdins (7).This publication has 7 references indexed in Scilit:
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