Chaotic behavior in dopamine neurodynamics.

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Abstract
The dynamics of a model of the central dopaminergic neuronal system are reported. For certain values of a parameter .hivin.k, which monitors the efficacy of dopamine at the postsynaptic receptor, chaotic solutions of the dynamical equations appear.sbd.a prediction that correlates with the observed increased variability in behavior among schizophrenics, the rapid fluctuations in motor activity among Parkinsonian patients treated chronically with L-dopa, and the lability of mood in some patients with an affective disorder. The hypothesis offers specific results concerning the appearance or disappearance of erratic solutions as a function of .hivin.k and the external input to the dopamine neuronal system.