Benzimidazole derivatives as novel nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 1: Benzimidazole-5-sulfonamides
- 1 February 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (3) , 799-803
- https://doi.org/10.1016/j.bmcl.2004.10.089
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Design and Structure−Activity Relationships of 2-Alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl)imidazolo[1,2-a]pyrimid-5-ones as Potent GnRH Receptor AntagonistsJournal of Medicinal Chemistry, 2003
- Discovery of a Thieno[2,3-d]pyrimidine-2,4-dione Bearing a p-Methoxyureidophenyl Moiety at the 6-Position: A Highly Potent and Orally Bioavailable Non-Peptide Antagonist for the Human Luteinizing Hormone-Releasing Hormone ReceptorJournal of Medicinal Chemistry, 2002
- 2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chainBioorganic & Medicinal Chemistry Letters, 2002
- Applications for GnRH antagonists.Trends in Endocrinology & Metabolism, 2001
- Chemistry and Molecular Biology in the Search for New LHRH AntagonistsAngewandte Chemie International Edition in English, 1997
- GnRH Agonists and AntagonistsDrugs, 1988
- Gonadotropin-Releasing Hormone Analog Design. Structure-Function Studies Toward the Development of Agonists and Antagonists: Rationale and PerspectiveEndocrine Reviews, 1986
- Synthetic analogs of luteinizing hormone releasing hormone (LH-RH) substituted in position 6 and 10Biochemical and Biophysical Research Communications, 1974
- Gonadotropin-Releasing Hormone: One Polypeptide Regulates Secretion of Luteinizing and Follicle-Stimulating HormonesScience, 1971
- Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequenceBiochemical and Biophysical Research Communications, 1971