Neuropeptides in temporomandibular joints with rheumatoid arthritis: a clinical study
- 1 December 1991
- journal article
- Published by Wiley in European Journal of Oral Sciences
- Vol. 99 (6) , 519-521
- https://doi.org/10.1111/j.1600-0722.1991.tb01063.x
Abstract
— There is evidence that neuropeptides play a role in the development of arthritis. Synovial fluid from arthritic temporomandibular joints in patients with rheumatoid arthritis was therefore investigated for presence of the neuropeptides calcitonin gene‐related peptide, substance P, neurokinin A and neuropeptide Y. All four peptides were found in the synovial fluid above plasma level, but calcitonin gene‐related peptide showed the highest concentration and substance P the lowest.Keywords
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