Antileishmanial activity of mycobacillin.
- 31 December 1976
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 30 (3) , 262-266
- https://doi.org/10.7164/antibiotics.30.262
Abstract
Mycobacillin, a cyclic polypeptide antifungal antibiotic effectively inhibits the growth of promastigote form of the protozoal organism, Leishmania donovani, strain 81 in liquid medium. O2 uptake by intact cells of the protozoa with exogenous glucose is appreciably reduced within 30 min in the presence of the antibiotic at a concentration of 15 .mu.g/ml. Appreciable leakage of intracellular 260 and 280 nm absorbing materials takes place from the protozoan cells incubated with the antibiotic at similar concentration.This publication has 2 references indexed in Scilit:
- Amino acid sequence in mycobacillinBiochemical Journal, 1960
- DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTIONJournal of Biological Chemistry, 1949