AN INVESTIGATION IN MAN INTO THE RELATIVE POTENCY OF LIGNOCAINE, BUPIVACAINE AND ETIDOCAINE
- 1 May 1975
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 47 (5) , 586-591
- https://doi.org/10.1093/bja/47.5.586
Abstract
The relative potency of lignocaine, bupivacaine and etidocaine was estimated by forearm skin weals in four volunteers. Potency was estimated as the time to half-recovery of a sharp sensation in response to a needle-prick. The increase in duration of action with increased concentration was greater for bupivacaine and etidocaine as compared with lignocaine. At the same concentrations, bupivacaine had a longer duration of action than etidocaine. However, etidocaine 1% had a longer duration of action than bupivacaine 0.5%.Keywords
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