Enantioselective Pharmacokinetics of dl-threo-Methylphenidate in Humans
- 1 January 1993
- journal article
- clinical trial
- Published by Springer Nature in Pharmaceutical Research
- Vol. 10 (1) , 14-21
- https://doi.org/10.1023/a:1018956526016
Abstract
A definitive enantioselective pharmacokinetic evaluation of dl-threo-methylphenidate (MPH) was carried out in 11 healthy volunteers, all of whom received, in a randomized crossover design, three oral...Keywords
This publication has 31 references indexed in Scilit:
- Stereoselective Urinary Pharmacokinetics of dl-threo-Methylphenidate and Its Major Metabolite in HumansJournal of Pharmaceutical Sciences, 1992
- The absorption of sustained‐release methylphenidate formulations compared to an immediate‐release formulationBiopharmaceutics & Drug Disposition, 1989
- Effects of Methylphenidate Dosage in Hyperactive Reading-disabled Children: I. Behavior and Cognitive Performance EffectsJournal of the American Academy of Child & Adolescent Psychiatry, 1988
- Development of enantioselective gas chromatographic quantitation assay for dl-threo-methylphenidate in biological fluidsJournal of Chromatography B: Biomedical Sciences and Applications, 1986
- Importance of Drug Enantiomers in Clinical PharmacologyDrugs, 1985
- Slow-release methylphenidate: problems when children chew tablets.1984
- Methylphenidate Hydrochloride Given With or Before Breakfast: II. Effects on Plasma Concentration of Methylphenidate and Ritalinic AcidPediatrics, 1983
- PHARMACOKINETICS OF METHYLPHENIDATE IN MAN, RAT AND MONKEY1983
- Metabolism and disposition of methylphenidate-14C: studies in man and animals.1974
- Conformational similarities between molecular models of phenethylamine and of potent inhibitors of the uptake of tritiated norepinephrine by adrenergic nerves in rabbit aorta.1970