Abstract
ARTERIOGRAPHY is a valuable diagnostic procedure in the management of peripheral vascular disease. Although relatively infrequent, untoward reactions may occur after intra-arterial injections of contrast media. Varying degrees of pain and symptoms of ischemia are commonly observed, but fortunately only rarely does one see complications leading to tissue loss, particularly with the currently available diatrizoate group of contrast agents. A number of investigative works have been reported through the years on the vascular response to intra-arterial injections of contrast media. Some have emphasized the vasoconstrictive effects of the contrast agents,1,2 whereas others have minimized these effects.3 Concentration of the dyes, rapidity of injection, and degree of arterial occlusive disease present contribute to the occurrence of complications during arteriography. In this study, the phasic and mean arterial flow and changes in pressure or pulse volume were measured during arteriography in both dog and man. Additional studies were made with

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