Promotion of Bone Calcification by Sodium Fluoride: Short-Term Experiments on Newborn Rats Using Tetracycline Labeling
- 1 February 1966
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 83 (2) , 162-170
- https://doi.org/10.1001/archotol.1966.00760020164019
Abstract
In young rats, NaF in optimum doses promotes Ca deposition in bone due to a depressing action on bone resorption, probably combined with a stimulating action on bone calcification. Experiments on rats demonstrating the positive skeletal Ca balance from the action of NaF indicates that it may become a therapeutic weapon in certain bone diseases to cause an excess of bone calcification over bone resorption.This publication has 3 references indexed in Scilit:
- Sodium Fluoride For Arrest of OtosclerosisArchives of Otolaryngology (1960), 1964
- The In Vivo Distribution of Tetracyclines in Canine BoneJournal of Bone and Joint Surgery, 1962
- PHARMACOLOGY AND THERAPEUTIC EFFICACY OF TETRACYCLINE1954