Treatment of Chlamydial Urethritis in Men and Chlamydia trachomatis-pos/f/Ve Female Partners

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Abstract
Men (71) who had C. trachomatis-positive nongonococcal urethritis were assigned randomly to treatment for 1 wk with either tetracycline or erythromycin (1 g daily). Of these men, 70 completed the study. At follow-up, there were 2 therapeutic failures among 36 patients treated with erythromycin, and 2 failures among 34 patients treated with tetracycline. Twenty-four C. trachomatis-positive female contacts were randomly assigned to treatment regimens similar to those of the men. There was 1 treatment failure among 12 women treated with erythromycin and no failure among 12 treated with tetracycline. The urethral smears contained < 5 leukocytes per high-power field in 16% of the C. trachomatis-positive men with symptoms suggestive of urethritis.

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