Mechanism of Paraquat Toxicity in Lung and its Relevance to Treatment
- 1 January 1987
- journal article
- review article
- Published by SAGE Publications in Human Toxicology
- Vol. 6 (1) , 31-36
- https://doi.org/10.1177/096032718700600105
Abstract
1 The symptoms of paraquat poisoning depend largely on the amount of compound consumed, although in many cases the most characteristic feature of poisoning is lung damage, causing severe anoxia which leads to death.Keywords
This publication has 22 references indexed in Scilit:
- Structural requirements of compounds to inhibit pulmonary diamine accumulationBiochemical Pharmacology, 1983
- Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administrationBiochemical Pharmacology, 1982
- Inhibition of paraquat accumulation in rat lung slices by a component of rat plasma and a variety of drugs and endogenous aminesBiochemical Pharmacology, 1976
- A mechanism of paraquat toxicity in mice and ratsToxicology and Applied Pharmacology, 1976
- The rates of radical formation from the dipyridylium herbicides paraquat, diquat, and morfamquat in homogenates of rat lung, kidney, and liver: An inhibitory effect of carbon monoxideToxicology and Applied Pharmacology, 1975
- Pulmonary effects of paraquat in the first day after injectionAmerican Journal of Physiology-Legacy Content, 1975
- Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicityBiochemical and Biophysical Research Communications, 1974
- Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicidesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1973
- The action of paraquat and diquat on the respiration of liver cell fractionsBiochemical Journal, 1968
- Potentiometric Studies on SemiquinonesJournal of the American Chemical Society, 1933