Cancer Regression by Senescence
- 10 May 2007
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 356 (19) , 1996-1997
- https://doi.org/10.1056/nejmcibr071461
Abstract
Experiments in mouse models of lymphoma, sarcoma, and hepatocarcinoma indicate that targeting p53 may be a sensible therapeutic strategy and that cellular senescence contributes to tumor regression.Keywords
This publication has 4 references indexed in Scilit:
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- Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomasNature, 2007
- Modeling the Therapeutic Efficacy of p53 Restoration in TumorsCell, 2006
- The power and the promise of oncogene-induced senescence markersNature Reviews Cancer, 2006