An energy sensor for control of energy intake
Open Access
- 1 March 1997
- journal article
- review article
- Published by Cambridge University Press (CUP) in Proceedings of the Nutrition Society
- Vol. 56 (1A) , 41-50
- https://doi.org/10.1079/pns19970008
Abstract
Control of energy intake, either in response to changes in the energy content of food or in energy expenditures and storage, is based on the detection of a feedback signal generated in the processing of metabolic fuels for energy. Evidence from studies of the fructose analogue, 2,5-AM, indicates a sensor in liver responds to changes in intracellular ATP or some closely associated event and communicates this information to the brain via vagal afferent neurons. Such a mechanism could serve as the energy sensor which controls energy intake.Keywords
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