Activation of human leucocyte procollagenase by rheumatoid synovial tissue culture medium.
Open Access
- 1 December 1975
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 34 (6) , 520-523
- https://doi.org/10.1136/ard.34.6.520
Abstract
Production of a factor activating leucocyte procollagenase by tissue culture of rheumatoid synovium was shown. The activator was isolated, partly purified, and shown to be thermolabile, nondialysable, and had no activity toward casein, haemoglobin, histones, and PZ-peptide. The activity of the activator was partly decreased by trypsin.Keywords
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