Abstract
This study investigated the histogenesis of the Kaposi''s sarcomas occurring in young homosexual men. Paraffin sections of 7 tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Hypothetically, both components of Kaposi''s sarcoma are of endothelial cell origin.

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