Effect of Live Measles Vaccine on the Platelet Count

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Abstract
THROMBOCYTOPENIA may accompany or follow a variety of viral infections.1 Thrombocytopenic purpura is a well recognized but apparently uncommon complication of measles.2 , 3 The availability of an attenuated live measles vaccine allowed a study of the effects of a controlled viral infection on the platelet count. This study demonstrates that a prompt, transient, mild depression of the platelet count occurs in many cases after inoculation with live measles virus.Materials and MethodsSubjectsSubjects, both males and females, ranged in age from six weeks to thirty-nine years. All were afebrile and in good health at the time of vaccination. Twenty-nine were . . .

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