Mitoxantrone hydrochloride (NSC-310739) in lymphoma
- 1 March 1983
- journal article
- research article
- Published by Springer Nature in Investigational New Drugs
- Vol. 1 (1) , 65-70
- https://doi.org/10.1007/bf00180193
Abstract
The members of the Southwest Oncology Group have treated thirteen patients with Hodgkin's disease and thirty-seven with non-Hodgkin's lymphoma with mitoxantrone on the every three week schedule. While the result (\313 responses in Hodgkin's; \937 responses in non-Hodgkin's lymphoma) is not striking, there is a definite antitumor activity in a very heavily pretreated group of patients. Toxicity was acceptable. Additional trials in lymphoma are planned using mitoxantrone in combination with BCNU.Keywords
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