Sustained Complete Remission of Metastatic Sweat Gland Carcinoma

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Abstract
CARCINOMAS of the eccrine sweat glands are rare tumors that, once metastatic, generally have a poor prognosis.1-7When primary surgery has failed to control the disease, radiotherapy has been of little additional benefit.6Insufficient data are available to permit an assessment of the effectiveness of systemic chemotherapy. Hyperthermic perfusion with chemotherapy8has been successfully employed as an aggressive means of treating other cancers of the extremities, which avoids the need for amputation. Using this technique, a sustained complete remission was induced in a patient with an eccrine porocarcinoma of the right foot with multiple metastases to the entire leg. There was complete rehabilitation. Report of a Case A small sore between the right fourth and fifth toes developed in a 60-year-old man. It was treated with a variety of topical medications and allowed by the patient to grow, during a two-year period, into a large fungating mass.

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