THE DISTRIBUTION OF ANTIGENIC DETERMINANTS IN RAT SKIN COLLAGEN
Open Access
- 1 June 1971
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 133 (6) , 1309-1324
- https://doi.org/10.1084/jem.133.6.1309
Abstract
Immunological studies of rat skin collagen were carried out with a sensitive and quantitative radioimmunoassay. Hyperimmune rabbit antisera to rat skin collagen and isolated α2 chains were used. Iodine-labeled α chains and CNBr-produced peptides served as test antigens, and native collagen, α chains, and CNBr peptides were employed as inhibitors in the assay.Keywords
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