The Effect of Dietary Protein Levels on the Rate of Lipid Biosynthesis from Glycerol-3-Phosphate in Rat Liver
- 1 January 1975
- journal article
- research article
- Published by S. Karger AG in Annals of Nutrition and Metabolism
- Vol. 18 (2) , 70-78
- https://doi.org/10.1159/000175578
Abstract
The effect of dietary protein levels on the rate of lipid synthesis from glycerol-3-phosphate was studied in the rat. Optimal conditions for studying this metabolic reaction were established by measuring the entry of sn-14C-glycerol-3-phosphate into lipid in vitro. The rate of glycerol-3-phosρhate incorporation into lipid in animals fed a 10 % protein diet for 6 days was significantly less than for those given diets containing 20 or 30 % protein while the converse was true after 26 days. The results indicate that the response of this particular metabolic step in lipid formation to dietary protein should be considered when attempting to explain the influence of dietary protein on lipid concentration in various tissues.Keywords
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