Abstract
HeadacheHeadache, a vague, subjective symptom, often encountered, but difficult to evaluate, seems to occur quite frequently in the myxedematous patient although the underlying mechanism is not clear. The headache is usually described as chronic, recurrent, bilateral and diffuse, and quite unlike sinusitis, migraine, eyestrain and the incidental headache. In the Georgetown series 14 per cent of 109 patients complained of headache.It is admitted that most of the studies incriminating headache and myxedema are purely clinical observations, lacking adequate controls, satisfactory diagnostic criteria and clear historical delineation from other types of headache.78 , 79 For example, Jones80 excluded all the usual . . .

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