ACTION OF SYMPATHOMIMETIC DRUGS ON THE ISOLATED JUNCTION OF THE BILE DUCT AND DUODENUM

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Abstract
The actions of adrenaline, noradrenaline and phenylephrine were studied both on the terminal tract of bile duct (prepared as spiral strips or intact) and on the adjacent duodenum taken from the calf and the cat. These amines contract the terminal bile duct and relax the duodenum. Furthermore, on the basis of the action of some adrenaline antagonists, the hypothesis is advanced that there are α-receptors which mediate contraction of muscle in the sphincterial zone of the bile duct.