Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding.
Open Access
- 1 February 1994
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 269 (6) , 3976-3984
- https://doi.org/10.1016/s0021-9258(17)41730-3
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- Structure-function relationship of basic fibroblast growth factor: Site-directed mutagenesis of a putative heparin-binding and receptor-binding regionBiochemical and Biophysical Research Communications, 1992
- Release of cell surface‐associated basic fibroblast growth factor by glycosylphosphatidylinositol‐specific phospholipase CJournal of Cellular Physiology, 1992
- Effect of heparin on the binding affinity of acidic FGF for the cloned human FGF receptors, flg and bekBiochemical and Biophysical Research Communications, 1990
- Disulfide Bonds are Neither Required, Present, Nor Compatible with Full Activity of Human Recombinant Acidic Fibroblast Growth FactorGrowth Factors, 1990
- Basic fibroblast growth factor is released from endothelial extracellular matrix in a biologically active formJournal of Cellular Physiology, 1989
- Tumor Formation Dependent on Proteoglycan BiosynthesisScience, 1988
- Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitroBiochemical and Biophysical Research Communications, 1988
- A form of human basic fibroblast growth factor with an extended amino terminusBiochemical and Biophysical Research Communications, 1987
- Effect of heparin on the stimulation of non-vascular cells by human acidic and basic FGFBiochemical and Biophysical Research Communications, 1986
- Human brain-derived acidic and basic fibroblast growth factors: Amino terminal sequences and specific mitogenic activitiesBiochemical and Biophysical Research Communications, 1986