Organization and expression of rat Tspy
- 1 July 1998
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 83 (3-4) , 270-274
- https://doi.org/10.1159/000015169
Abstract
We have isolated both a full-length rat Tspy cDNA from testicular mRNA by rapid amplification of cDNA ends (RACE) and RT-PCR and a full-length rat Tspy gene from genomic DNA by PCR. In contrast to the mouse, where Tspy is present in a single copy and is apparently functionless, and to man and cattle, where TSPY is organized in a moderately repetitive cluster, the rat Tspy locus apparently consists of one complete functional and one truncated, probably nonfunctional, copy, coherently localized on Yp, as revealed by FISH analysis.Keywords
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