Toxins Acting on the Cytoskeleton

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ABBREVIATIONS: CTSK, cytoskeleton; MT, microtubules; MF, microfilaments; IF, intermediate filaments; MW, molecular weight; MAP, microtubule-associated protein; GTP, guanosine triphosphate; SDS-PAGE, sodium dodecylsulfate polyacrylamide gel electrophoresis; MTOC, microtubule organizing center; G-actin, monomeric globular actin; F-actin, polymeric filamentous actin; ATP, adenosine triphosphate; ABP, actin binding protein; IFAP, intermediate filament associated protein; GFAP, glial fibrillary acidic protein; CHO, Chinese hamster ovary; DMSO, dimethyl sulfoxide; MBC, methyl benzimidazole-2-yl carbamate; EMP, estramustine phosphate; NAD, nicotinamide adenine dinucleotide; CB, CD, CE, cytochalasins B, D and E; EM, electron microscopy; DNA, deoxyribonucleic acid; mRNA, messenger ribonucleic acid; DNAse I, deoxyribonuclease I; ATPase, adenosine triphosphatase; K, kilodalton; HEp-2 cells, human epithelial larynx carcinoma cells; CNF, cytotoxic necrotizing factor of E.coli;. TPA, 12-O-tetradecanoylphorbol-13-acetate=phorbol myris tate acetate; cAMP, adenosine 3'5'-cyclic monophosphate; NF, neurofilament; 2,5-HD, 2,5-hexanedione; TriEL, triethyl lead chloride.

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