PEMPHIGUS VULGARIS

Publisher Website
Google Scholar
Abstract
DIFFERNTIAL diagnosis of the generalized bullous diseases is difficult, especially when individual cases are observed initially or for a short time. As Ormsby and Montgomery1 state The term pemphigus was formerly applied to every disease of the skin presenting bullae. As knowledge has increased the group has been greatly reduced. The problem is not yet entirely settled, as certain types of multiform erythema and dermatitis herpetiformis are difficult to distinguish from pemphigus. The differentiation of pemphigus vulgaris from the two bullous diseases resembling it most closely, dermatitis herpetiformis and erythema bullosum, is important from at least two viewpoints. First is that of prognosis, a fatal outcome being expected in pemphigus vulgaris. Second is that of drawing conclusions from the responses to therapeutic trials of antibiotics and hormones, such as corticotropin (ACTH) and the adrenal steroids. Obviously, a therapeutic success has entirely different and greater significance when there is

This publication has 2 references indexed in Scilit: