Fast and sensitive multiple sequence alignments on a microcomputer
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 5 (2) , 151-153
- https://doi.org/10.1093/bioinformatics/5.2.151
Abstract
A strategy is described for the rapid alignment of many long nucleic acid or protein sequences on a microcomputer. The program described can handle up to 100 sequences of 1200 residues each. The approach is based on progressively aligning sequences according to the branching order in an initial phylogenetic tree. The results obtained using the package appear to be as sensitive as those from any other available method.Keywords
This publication has 6 references indexed in Scilit:
- Optimal alignments in linear spaceBioinformatics, 1988
- A strategy for the rapid multiple alignment of protein sequencesJournal of Molecular Biology, 1987
- Progressive sequence alignment as a prerequisitetto correct phylogenetic treesJournal of Molecular Evolution, 1987
- Multiple sequence alignment by a pairwise algorithmBioinformatics, 1987
- A multiple alignment program for protein sequencesBioinformatics, 1987
- Rapid similarity searches of nucleic acid and protein data banks.Proceedings of the National Academy of Sciences, 1983