Vitamin K
- 19 January 1940
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 91 (2351) , 58-62
- https://doi.org/10.1126/science.91.2351.58
Abstract
During the decade following Dam's first observations on the hemorrhagic syndrome the combined efforts of several groups of investigators have solved many of the important problems connected with the new vitamin. Sources of vitamin K were discovered, methods of extraction and purification devised, the isolation effected, the structure of K1 worked out and then verified by synthesis, and a promising start made on the therapeutic applications. In addition, simple water soluble compounds with antihemorrhagic properties have been supplied for clinical work. Preliminary results with these compounds are encouraging.Keywords
This publication has 39 references indexed in Scilit:
- THE CONSTITUTION AND SYNTHESIS OF VITAMIN K1Journal of the American Chemical Society, 1939
- SYNTHESIS OF ANTIHEMORRHAGIC COMPOUNDSJournal of the American Chemical Society, 1939
- QUINONES HAVING VITAMIN K ACTIVITYJournal of the American Chemical Society, 1939
- SIMPLE COMPOUNDS WITH VITAMIN K ACTIVITYJournal of the American Chemical Society, 1939
- DERIVATIVES OF VITAMINS K1 AND K2Journal of the American Chemical Society, 1939
- Isolierung des Vitamins K in hochgereinigter FormHelvetica Chimica Acta, 1939
- Vitamin K aus AlfalfaHelvetica Chimica Acta, 1939
- Synthesis of the Antihemorrhagic Vitamin by BacteriaExperimental Biology and Medicine, 1938
- PROTHROMBIN DEFICIENCY THE CAUSE OF BLEEDING IN BILE FISTULA DOGSThe Journal of Experimental Medicine, 1936
- A "Scurvy-Like" Disease in ChicksScience, 1933