The bottom line for prediction of residue solvent accessibility.
Open Access
- 1 December 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Protein Engineering, Design and Selection
- Vol. 12 (12) , 1051-1054
- https://doi.org/10.1093/protein/12.12.1051
Abstract
A simple method of predicting residue solvent accessibilities in proteins is described, with the intention that it should be used as a baseline by which more sophisticated approaches to prediction can be judged. Comparison with existing methods of predicting residue burial reveals that their performance is often little better than that of the baseline method. The problem of comparing different prediction methods is shown to be complicated by the proliferation of different schemes for classifying residue burial.Keywords
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