Localization of a Low Molecular Weight Protease Inhibitor to Tracheal and Maxillary Sinus Mucosa
- 1 January 1977
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 358 (1) , 425-430
- https://doi.org/10.1515/bchm2.1977.358.1.425
Abstract
Normal human bronchial secretion contains protease inhibitors from plasma and an acid-stable, low MW inhibitor which strongly inactivates granulocyte elastase and chymotrypsin-like cationic proteins. The distribution of this bronchial protease inhibitor in tracheal mucosa was analyzed by an indirect immunoperoxidase method. Strong peroxidase staining was obtained in the columnar ciliated epithelium of the trachea and in the sero-mucus glands. The findings support to a local mucosal production of the inhibitor. Maxillary sinus mucosa was also positively stained for the inhibitor.This publication has 5 references indexed in Scilit:
- The Interactions between a Low Molecular Weight Protease Inhibitor of Bronchial Mucus and Chymotrypsin-like Cationic Proteins of GranulocytesHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1977
- Clinica Chimica Acta; International Journal of Clinical Chemistry, 1976
- Localization of Seminal Plasma Proteinase Inhibitors in Human Spermatozoa as Revealed by the Indirect Immunofluorescence TechniqueHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1976
- Inhibition of Elastase from Granulocytes by the Low Molecular Weight Bronchial Protease InhibitorScandinavian Journal of Clinical and Laboratory Investigation, 1976
- Cationic Proteins of Human Granulocytes V. Interaction with Plasma Protease InhibitorsScandinavian Journal of Clinical and Laboratory Investigation, 1975