Abstract
IN an early report on the use of APF (Animal Protein Factor) supplements in swine rations Cunha et al. (1950) suggested that the protein requirements of swine might need to be re-evaluated using adequate amounts of vitamin B12, plus other factors present in Lederles' APF supplement. Jukes et al. (1950) showed that chlortetracycline (Aureomycin) was largely responsible for the increased rate of gain of growing swine fed this APF supplement. It has since been reported by Catron and coworkers (1952) that corn-soybean oil meal type diets adequate in non-protein dietary factors and containing a 14-11-8 percent protein combination were equal to a 16-13-10 percent combination for pigs from weaning to 75, 75 to 150 and 150 to 200 lb. when chlortetracycline was added to the lower level protein combination. These workers and Burnside et al. (1954) suggested that antibiotic apparently effected a protein-sparing action with respect to the pigs' protein needs. Robison (1952), Bowland and McElroy (1952) and Botkin et al. (1951) have reported experiments in which lower protein diets supplemented with an antibiotic were equal or superior to higher protein diets without an antibiotic. Copyright © . .