Abstract
Ferrokinetic and morphologic methods were employed to study the endotoxin-induced shift in erythropoiesis from the bone marrow to the spleen. This phenomenon is dose dependent in respect to both magnitude of response and duration of response. It is also reversible. The results are consistent with the hypothesis that leukocytic hyper-plasta of the bone marrow may play an important role in the shunting of erythropoiesis from the bone marrow to the spleen.

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