Abstract
By means of fluorescein-labelled antibody, the primary atypical pneumonia virus was found to multiply exclusively in the cytoplasm of the epithelial cells lining the bronchioles and air sacs of developing chick embryos. When 13-day old embryos were inoculated intra-amniotically and incubated at 35°C. for 5 days or longer, over 90 per cent of the inoculated embryos became infected.