Stereoselective synthesis of α-methylene-β-hydroxy-γ-alkoxy esters from α-alkoxy aldehydes
- 1 January 1983
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 1112-1113
- https://doi.org/10.1039/c39830001112
Abstract
The Reformatsky-type condensation between methyl and t-butyl 3-(N,N-dimethylamino)propionates (9) and (10) with α-alkoxy aldehydes, which has been studied on varying the protective group of the aldehyde, proceeds with good diastereoselectivity.Keywords
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