Human Herpesvirus 6 Latently Infects Early Bone Marrow Progenitors In Vivo
- 1 January 1999
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 73 (1) , 754-9
- https://doi.org/10.1128/jvi.73.1.754-759.1999
Abstract
We have studied the in vivo tropism of human herpesvirus 6 (HHV-6) for hemopoietic cells in patients with latent HHV-6 infection. Having used a variety of cell purification, molecular, cytogenetic, and immunocytochemical procedures, we report the first evidence that HHV-6 latently infects early bone marrow progenitor cells and that HHV-6 may be transmitted longitudinally to cells which differentiate along the committed pathways.Keywords
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