Immunologic Aspects of Chronic Obstructive Pulmonary Disease
Top Cited Papers
- 4 June 2009
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 360  (23) , 2445-2454
- https://doi.org/10.1056/nejmra0804752
Abstract
This review is an account of how pulmonary damage caused by cigarette smoke and other environmental toxins can incite inflammatory and immunologic reactions that culminate in chronic obstructive pulmonary disease (COPD). The authors present evidence that autoimmunity has a role in the development of COPD.Keywords
This publication has 89 references indexed in Scilit:
- The Foxp3+ regulatory T cell: a jack of all trades, master of regulationNature Immunology, 2008
- Autoantibodies in Patients with Chronic Obstructive Pulmonary DiseaseAmerican Journal of Respiratory and Critical Care Medicine, 2008
- CC Chemokine Receptor 5 and CXC Chemokine Receptor 6 Expression by Lung CD8+ Cells Correlates with Chronic Obstructive Pulmonary Disease SeverityThe American Journal of Pathology, 2007
- Translational Mini-Review Series on Toll-like Receptors:
Networks regulated by Toll-like receptors mediate innate and adaptive immunityClinical and Experimental Immunology, 2007
- Framingham Heart Study genome-wide association: results for pulmonary function measuresBMC Medical Genetics, 2007
- Toll-like receptors in systemic autoimmune diseaseNature Reviews Immunology, 2006
- State of the Art. Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary PerspectiveProceedings of the American Thoracic Society, 2006
- An Immune Basis for Lung Parenchymal Destruction in Chronic Obstructive Pulmonary Disease and EmphysemaPLoS Medicine, 2004
- Increased expression of nuclear factor-ÎşB in bronchial biopsies from smokers and patients with COPDEuropean Respiratory Journal, 2002
- The Relations between Structural Changes in Small Airways and Pulmonary-Function TestsNew England Journal of Medicine, 1978