Sensitivity Improvement of a Moving Wire Liquid Chromatography Detector
- 1 January 1972
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 10 (1) , 31-34
- https://doi.org/10.1093/chromsci/10.1.31
Abstract
The sensitivity of a moving wire flame ionization detector for liquid chromatography has been enhanced by a factor of 20 to 50 by spraying the column effluent on the wire instead of coating from a block. At the same time the troublesome “spike-effect” has been eliminated and the split ratio (part of the solute deposited on the wire) no longer depends on the effluent flow rate, which means that peak areas have become independent of the flow rate.Keywords
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