2-Phenethylimidazole derivatives. Synthesis and antimycotic properties
- 1 May 1975
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 18 (5) , 530-533
- https://doi.org/10.1021/jm00239a022
Abstract
Compounds of type (X = O, NH; Ar and Ar' = phenyl of substituted phenyl; ten examples) were prepared and assayed against miconazole (II,X = O; Ar = Ar' =2,4-Cl2C6H3) as potential antimycotic agents. Optimal activity was noted for I(X = O; Ar = Ar' = 2,4-Cl2C6H3), the direct analog of miconazole. It is about one-tenth as active.Keywords
This publication has 0 references indexed in Scilit: