HLA-DR specificities among Japanese with several autoimmune diseases

Publisher Website
Google Scholar
Abstract
HLA—A,—B,—C, and—DR antigens were determined in order to study the association of HLA in Japanese patients with several autoimmune diseases, hypertrophic cardiomyopathy, and Hodgkin's disease. The frequency of HLA—DR4 was significantly increased in the patients with rheumatoid arthritis, juvenile‐onset insulin‐dependent diabetes mellitus (IDDM) and hypertrophic obstructive cardiomyopathy. In this study, no significant associations with A, B, or C specificities were observed except BW22 in IDDM. In contrast, the negative association with HLA—DR2 was observed in Hashimoto's thyroiditis, pemphigus vulgaris and hypertrophic non‐obstructuve cardiomyopathy.

This publication has 11 references indexed in Scilit: