Drug Resistance of Bacteria

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Abstract
DRUG resistance of bacteria is a major medical problem because it severely limits the usefulness of virtually all known antimicrobial agents and often necessitates the administration of highly toxic durgs when the more acceptable ones are found to be ineffective. Occasionally, cultures from patients with bacterial infections yield organisms resistant to all the drugs used in sensitivity tests. The following remarks pertain primarily to currently practical aspects of the general problem. Few clinically applicable suggestions have yet emerged from recent studies of the mechanisms of resistance and its genetic control; accordingly, these interesting subjects are only briefly summarized here. Extent . . .

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