Increased Glomerular Filtration Rate in Kidney-Transplant Recipients Who Take Sildenafil
- 1 June 2000
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 342 (22) , 1679-1680
- https://doi.org/10.1056/nejm200006013422217
Abstract
Sildenafil is a potent inhibitor of guanosine 3',5'-cyclic monophosphate (cGMP)–specific phosphodiesterase.1,2 It is being used increasingly by male kidney-transplant recipients for erectile dysfunction,3,4 but its effects on the grafted kidney have not, to our knowledge, been examined.Keywords
This publication has 4 references indexed in Scilit:
- Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidneyKidney International, 1999
- Oral Sildenafil in the Treatment of Erectile DysfunctionNew England Journal of Medicine, 1998
- Sildenafil, a novel effective oral therapy for male erectile dysfunctionBritish Journal of Urology, 1996
- Cyclic nucleotide phosphodiesterases: functional implications of multiple isoformsPhysiological Reviews, 1995