The Encephautogenic Dose Response in Guinea Pigs of the Tryptophan Region of Myelin Basic Protein
- 1 January 1974
- journal article
- research article
- Published by Taylor & Francis in Immunological Communications
- Vol. 3 (3) , 219-226
- https://doi.org/10.3109/08820137409057319
Abstract
The encephalitogenic dose response for the synthetic tryptophan peptide from the basic protein of myelin is given. The best dose in guinea pigs for disease induction using the peptide is between 1 and 3üg. Using doses higher or lower induces EAE in fewer animals.Keywords
This publication has 10 references indexed in Scilit:
- Encephalitogenic Activity of Peptides from the Smaller Basic Protein of Rat MyelinThe Journal of Immunology, 1973
- Experimental Allergic Encephalomyelitis (E.A.E.): Synthesis of the 7–11, 11–20, and 12–20 Peptides of Human Encephalitogenic Protein and Inhibition of Histological E.A.E. by the 12–20 PeptideCanadian Journal of Biochemistry, 1972
- Allergic Encephalomyelitis in Monkeys Induced by a Peptide from the A1 ProteinProceedings of the National Academy of Sciences, 1972
- Biological Activity and Synthesis of an Encephalitogenic DeterminantScience, 1971
- Encephalitogenic activity in rabbits of the C‐terminal region of bovine basic myelin proteinEuropean Journal of Immunology, 1971
- Essential Chemical Requirements for Induction of Allergic EncephalomyelitisNature, 1971
- Experimental Allergic Encephalomyelitis: Synthesis of Disease-Inducing Site of the Basic ProteinScience, 1970
- Allergic encephalomyelitis: Enzymatic degradation of the encephalitogenic basic protein from bovine spinal cordArchives of Biochemistry and Biophysics, 1969
- Maturation of human white matter myelin. Fractionation of the myelin membrane proteinsBiochemistry, 1968
- Solid Phase Peptide Synthesis. II. The Synthesis of BradykininJournal of the American Chemical Society, 1964