The Relationship of Fibrocystic Disease to Carcinoma of the Breast
- 1 October 1959
- journal article
- research article
- Published by American Medical Association (AMA) in A.M.A. Archives of Surgery
- Vol. 79 (4) , 670-678
- https://doi.org/10.1001/archsurg.1959.04320100136023
Abstract
Since the publication of lectures by Sir Astley Cooper,9Brodie,4and the classic observations made by Reclus,25numerous reports have appeared in the literature on the relationship of fibrocystic disease to carcinoma of the breast. The condition is referred to by various names—chronic cystic mastitis,20Schimmelbusch's disease,28adenocystic disease,1lobular hyperplasia,29simple cystic disease of the breast, and other designations.3,15,23,31Convincing proof that this disease is pathologically related to carcinoma has not been established. The uncertainty and varied ambiguous premises advanced relative to the malignant transformation of fibrocystic lesions of the breast have served as a stimulus for this report. Fibrocystic disease of the mammary glands is the commonest of all breast lesions and primarily affects females but may occur in males.18,30It is characterized clinically by pain or a lump in the breast and pathologically as a fibroglandular hyperplasia, localizedKeywords
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