Outcome of Unstable Angina in Patients with Diabetes Mellitus

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Abstract
This prospective hospital‐based, case–control study compares the outcome of unstable angina in non‐insulin dependent diabetic patients and non‐diabetic control subjects. One hundred and sixty‐two diabetic patients and 162 non‐diabetic control patients with unstable angina were entered into the study. The 3‐month mortality was 8.6 % (95 % confidence interval, CI = 4.4–12.9 %) in diabetic patients and 2.5 % (CI = 0.1–4.9 %) in control patients (p = 0.014). The 1‐year mortality was 16.7 % (CI = 10.9 %–22.4 %) in diabetic patients and 8.6 % (CI = 4.4 %–12.9 %) in non‐diabetic patients (p = 0.029). Diabetic patients received beta‐blockade and underwent coronary angiography and angioplasty less frequently than controls; the frequency of unstable angina, of acute myocardial infarction, and of coronary artery bypass grafting was similar in both groups at 1 year of follow‐up. It is concluded that diabetic patients with unstable angina have a higher mortality than non‐diabetic patients and that this difference is largely accounted for by early (first 3 months) mortality. © 1997 by John Wiley & Sons, Ltd.

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