Interaction of biofilm bacteria with antibiotics in a novel in vitro chemostat system
Open Access
- 1 October 1989
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 33 (10) , 1824-1826
- https://doi.org/10.1128/aac.33.10.1824
Abstract
Pseudomonas aeruginosa was cultivated at low growth rates under iron-limiting conditions on acrylic tiles. Biofilm cells exhibited increased tobramycin resistance compared with that of planktonic cells, and in old biofilms were more resistant than were cells in young biofilms. However, on suspension of the biofilm bacteria, glycocalyx-mediated resistance was lost.This publication has 18 references indexed in Scilit:
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