Effect of organic carbon on the uptake and toxicity of quaternary ammonium compounds to the fathead minnow, Pimephales promelas

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Abstract
The effect of dissolved organic, carbon on the uptake and toxicity of quaternary ammonium compounds was investigated with the fathead minnow, Pinephales promelas Aldrich humic acid (HA) reduced the toxicity of dioctadccyl dimethyl ammonium chloride (DODMAC) and monotallow trimethyl ammonium chloride (C1c 1gTMAC) but had no effect on the toxicity of tetradecyl trimethyl ammonium chloride (CgTMAC) dodecyl trimethyl ammonium chloride (C12, TMAC) or of octyl trimethyl ammonium chloride (CbTMAC) Aldrich HA also reduced the uptake rate constant of DODMAC and C16 12TMAC For DODMAC, the reduction in toxicity observed by Aldrich HA was similar to those observed with Suwannee River and Nordic Aquatic HAs and organic carbon from two river waters For C1c 1gTMAC Suwannee River and Nordic Aquatic HAs and river water organic carbon caused a significant amelioration of toxicity This amchoration of toxicity was quantitatively less than predicted based on Aldrich HA

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