Obesity, Regional Body Fat Distribution, and the Metabolic Syndrome in Older Men and Women

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Abstract
The metabolic syndrome is a complex disorder unifying dyslipidemia, insulin resistance, and hypertension. It is a primary risk factor for diabetes1 and cardiovascular disease.2 The overall prevalence of metabolic syndrome as defined by Adult Treatment Panel III guidelines3 in US adults is high (22%), and even higher among older men and women (42%).4 Physical inactivity, obesity, and diet composition all appear to be risk factors for the development of the metabolic syndrome.5 However, little is known concerning risk factors of the metabolic syndrome specific to older adults, who have a higher incidence of type 2 diabetes6,7 and cardiovascular disease8 than younger adults.

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