Expression of cellular oncogenes during embryonic and fetal development of the mouse.

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Abstract
Cellular oncogenes are conserved with great fidelity across a broad span of evolution. This avid conservation suggests possible roles in critical physiological functions. Little, however, is known about their activity in normal cellular processes. The expression pattern of 8 cellular oncogenes was examined during embryonic and fetal development of the mouse. Five of these genes (c-myc, c-erb, c-Ha-ras, c-src, and c-sis) were expressed at appreciable levels, and 4 were modulated in a consistent manner during the course of prenatal development.