Hematogenous origin of brain macrophages
- 1 June 1986
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 36 (6) , 844
- https://doi.org/10.1212/wnl.36.6.844
Abstract
Del Rio-Hortega believed that phagocytic cells in the CNS arise from microglia; however, recent autoradiographic studies have suggested a hematogenous origin for brain macrophages. To clarify this issue, we studied a young man with acute lymphoblastic leukemia and a peripheral white blood cell count of 22/mm3 who had an embolic brain infarct 2 weeks before he died. Macrophages were scarce within the lesion, suggesting that the principal phagocytic cell is hematogenous.This publication has 6 references indexed in Scilit:
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