Clostridial Gas Gangrene and Septicemia in Four Patients with Leukemia

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Abstract
FOUR cases of leukemia in which gas gangrene of the bowel and clostridial septicemia developed are reported. Ante-mortem blood cultures were positive in all, but 3 patients died before the diagnosis was established or therapy instituted. The fourth patient survived for four weeks after the positive blood culture, and in this case the clinical diagnosis of septicemia, possibly due to clostridium, was made and antibiotic therapy instituted. Similar cases in malignant neoplastic disease have recently been described.1 Case ReportsCase 1. A.S. (N.I.H. 01 02 84), a 36-year-old man with Schilling-type monocytic leukemia, was admitted to the Clinical Center on . . .